Despite advances in anti-retroviral therapy, HIV infection remains one of the biggest medical challenges so far. Understanding virus-host interactions is fundamental to the design of new anti-HIV drugs.
Highly active anti-retroviral therapy (HAART) has revolutionised the outcome of HIV infection. Highly expensive, HAART does not cure infection and presents with severe side effects including drug resistance. As a result, the need for designing novel effective drugs remains.
Further details: Immune system players against HIV