Lung cancer is the most common malignancy worldwide and is associated with poor prognosis. Re-evaluating the diagnostic criteria of different lung cancer subtypes to include specific steroid receptors should improve treatment and prognosis.
Gender seems to be a major determinant of lung cancer impact, histology, evolution, response to therapy and prognosis. This suggests a potential relation to steroid hormones, especially in view of the hormone replacement therapies and contraception strategies followed by a large proportion of the female population.
Further details: Revisiting lung cancer diagnosis: The role of steroid receptors