Materials transport across damaged artery walls

Atherosclerosis remains the single largest cause of death in the developed world. Looking at the way molecules pass through artery walls promises to show how to deliver drugs to tackle this disease.

The EU-funded LDLTRAPPING (Identifying causes of lipoprotein trapping in arteries) project has developed novel processes and algorithms to characterise water transport in the medial layer of the arterial wall. They also determined how the pressure pulse deforms the artery to reorganise the microstructure and cause local straining of the tissue.

Further details: Materials transport across damaged artery walls