The history of east-west church relations in the 14th century sheds light on the origins of conflict between different denominations. It also paves the way for more research on the topic in modern times.
For millennia, east and west have had very opposing religious persuasions, not only between Christianity and other religions, but within Christianity itself. In the Middle Ages, Catholicism and Orthodoxy vied for supremacy in the Mediterranean region, resulting in numerous conflicts and exchanges that could shed light even today on this still complex relationship. In this context, the Avignon Papacy, established in France from 1309 to 1377, played an important role in shaping east-west relations.
Further details: A closer look at the role of the Avignon Papacy in east-west relations