The treatment of cancer tumours is made complex by their microenvironment and the abnormalities of the blood vessels sustaining them. The EU-funded NeoNaNo project has developed methods to improve drug delivery to tumours and improve the efficacy of anticancer therapy.
Drug delivery to tumours is difficult. The blood vessels they depend on are abnormally structured, heterogeneously distributed and relatively poorly perfused, so transporting the drugs is challenging. Once the drugs have been delivered, the dense and hostile tumour microenvironment makes it hard to target them precisely.
Further details: New tools to boost the delivery of drugs to cancer tumours