Calcium homeostasis is central for many signalling pathways that function during development. European researchers shed light into the interplay between calcium signalling and other developmental pathways during cardiac development.
Calcium ions (Ca2+) play an instrumental role in cardiac biology – from excitation-contraction coupling to the regulation of hormone secretion and gene expression. Elucidating the interplay between major signalling pathways and electrochemical cues during embryogenesis is paramount for understanding normal and pathological heart development.
Further details: Molecular crosstalk during heart development