An EU initiative has performed pioneering research into the emerging field of quantitative and systems pharmacology (QSP).
To deliver new drugs, it is necessary to quantify, translate and simulate from the test tube to the patient. This includes modelling biological pathways, quantifying relationships between dose/exposure, target engagement, efficacy and safety in preclinical tests and humans, and utilising all relevant information efficiently and quantitatively. The creation and application of novel modelling methods to tackle current problems in drug development are dependent on the training of researchers with skills to perform these tasks.
Further information: Research and training network advances innovative approach to drug discovery and development