Glioblastoma is the most aggressive type of brain cancer with a dismal survival rate when treated with conventional therapy. The limited treatment options for this type of cancer demand concerted development efforts for new therapies.
Currently available anti-cancer therapies usually affect tumour progression only temporarily, and are accompanied by significant side effects. Cancer vaccination has emerged as an alternative therapeutic concept that aims at stimulating the patient’s immune system against the cancer. The activated T cells are able to specifically recognise the tumour cells and destroy them. Albeit personalised, previous approaches did usually not take into consideration the unique characteristics of each patient’s tumour.
Further details: Personalised vaccines against glioblastoma