The need to reduce animal testing of new drugs remains an important goal in biomedicine. Organs-on-chips are a very promising solution.
An organ-on-chip, created by microchip manufacturing methods, contains chambers that have cells flushed with fluid. Arranged to simulate tissue and organ level physiology, these microfluidic devices can mimic multicellular architectures, tissue-tissue interfaces and physicochemical microenvironments, and are vastly superior to conventional culture systems.
Further information: New developments in lab-on-chip to reduce animal testing