Researchers with the EU-funded SYSBIOFUN project have set out to describe the factors that influence our immune responses to fungal and bacterial infections.
Infections have shaped the human immune system, with genetic variability contributing to differing levels of susceptibility to infections. For example, fungi such as Candida albicans are ubiquitous colonisers of human skin and mucosa. Fungal pathogens like this invade the host when the host’s defence is diminished, and the combination of fungal and bacterial colonisation modulates mucosal and systemic immune responses.
Further information: Understanding human immune responses