Virus-like particles (VLPs) is an emerging technology with numerous biomedical applications such as drug delivery and vaccine development. Ongoing research into materials and surface engineering of VLPs is expected to expand their utilisation.
VLPs are synthetic nanostructures that emulate the conformation of viruses but completely lack infectivity. They rely on the inherent capacity of viral capsid proteins to self-assemble, offering an adaptable platform that can penetrate cells and deliver the desired content. Numerous studies have worked on determining which polymers associate best with viral proteins and their functionalisation capacity.
Further details: Engineered virus-like particles