Better probes for the proteome

Proteomics is the in-depth examination of protein behaviour. To advance research in this area, more sophisticated probes, binders, are needed to study health and disease.

Binders include antibody fragments and engineered scaffolds or aptamers (peptide molecules used to bind to a specific target molecule). Relevant applications for binders include microarrays for sorting and analysing information captured from analysis, multidimensional fluorescence imaging to study biological functioning, and proximity ligation, for observation of protein-protein interactions.

Further details: Better probes for the proteome