Assay standardisation is important for roadmapping vaccine technology. A European initiative standardised protocols and assays to improve the credibility of generated malaria vaccines.
Over the years, significant effort has been dedicated towards the development of candidate malaria vaccines derived from diverse novel technologies. The efficacy of specific surface parasite molecules as vaccine antigens depends on their ability to induce particular antibodies and immune protection in animals and humans. Individual groups have developed assays that measure the impact of the vaccine on parasite growth and virulence. However, these assays lack consistency and cannot be compared amongst the different groups, reducing the utility of the results.
Further details: Integration to speed-up malaria vaccine development