Researchers within the EU-funded NANOPHYS project create a complete picture of the cellular and subcellular properties of the fast-spiking, parvalbumin-expressing GABAergic basket cell, leading to far-reaching implications for clinical science and medicine.
Cortical neuronal networks are comprised of two types of neurons: Glutamatergic principal neurons and GABAergic interneurons. Although GABAergic interneurons numerically represent only 10-20 % of the neuronal population, they serve key functions in the network. However, in contrast to the substantial amount of information available on the subcellular signalling properties of pyramidal neurons, little was known about the properties of GABAergic interneurons.
Further details: New insights into the function of fast-spiking, parvalbumin+ GABAergic interneurons